MYC 靶向基因表达 PCR 芯片可用于研究由主要致癌转录因子控制的关键癌症相关的 84 个关键基因的表达。该芯片包含了 MYC 靶向调节诸如凋亡、细胞周期、细胞生长、增殖和分化、DNA 修复、表观遗传学、代谢、蛋白质合成、降解和周转、RNA 处理和信号转导等基本过程的基因。也包含了 MYC、MAX 和其他相关转录因子。利用该芯片，研究者可以方便并且可信地对与 MYC 调控相关的基因进行同时检测。

MYC & Co-Transcription Factors：E2F1, MAX, MAZ, MYCL, MYCN, PIAS2.

Up-Regulated by MYC：AIMP2, APEX1, ATF4, BAX, BCAT1, CAD, CBX3, CCNB1, CCND2, CCT5, CDC25A, CDK4, CHEK1, CKS2, CSTB, CTSC, DDX10, DKC1, E2F1, EIF4A1, EIF4B, EIF4E, ENO1, EXOSC8, FASN, GNL3, HK2, HNRNPA1, HNRNPA2B1, L TA4H, MAT2A, MGST1, MSH2, MTHFD1, NAP1L1, NBN, NCL, NME1(NM23), NOLC1, NPM1, ODC1, PA2G4, PAICS, PCNA, PHB, PO LD2, PPAT, PSMG1, PTEN, PYCR1, RPL13, RPL19, RPL23, RPL27A, RPL5, RPS5, SHMT1, SNRPB, SRM, SRSF1, TERT, TOP1, TP53(p53), TPI1, TYMS, UBE2C, YBX3.

Down-Regulated by MYC：CDKN1B (P27KIP1), CDKN2B (p15INK4b), CSDE1, ID3, ILK, ITGB1, MYC, PTPA, ZFP36L1.

Apoptosis：BAX, CCNB1, GNL3, NPM1, TP53 (p53).

Cell Cycle：CCNB1, CCND2, CDC25A, CDK4, CDKN1B(P27KIP1), CDKN2B(p15INK4b), GNL3, PA2G4, PCNA, TP53(p53).

Cell Growth & Proliferation：CDKN1B (P27KIP1), CKS2, NPM1, PA2G4, PCNA, PHB.

Chromatin Modifying & Associated Proteins：CBX3, NAP1L1.

DNA Repair：AIMP2, APEX1, CHEK1, MSH2, NBN, NPM1, PCNA, TERT, TP53 (p53).

DNA Replication：PCNA, POLD2, TOP1.

Extracellular Matrix (ECM) & Cell Adhesion Molecules：ILK, ITGB1.

Metabolism：BCAT1, CAD, ENO1, FASN, GCLC, HK2, LTA4H, MAT2A, MGST1, MTHFD1, NME1(NM23), ODC1, PAICS, PDK1, PPAT, PYCR1, SHMT1, SRM, TPI1, TYMS.

Protein Synthesis, Degradation & Turnover：CCT5, CSTB, CTSC, EIF4A1, EIF4B, EIF4E, NCL, NPM1, PSMG1, PYCR1, RPL13, RPL19, RPL23, RPL27A, RPL5, RPS5, UBE2C.

RNA Processing & Binding Factors：CSDE1, DDX10, DDX39B, DKC1, EXOSC8, HNRNPA1, HNRNPA2B1, NOLC 1, SNRPB, SRSF1.

Signal Transduction：ILK, NPM1, PDK1, PTEN, PTPA.

Transcription Factors & Cofactors：ATF4, ID3, MYC, TP53 (p53), YBX3, ZFP36L1.

Tumor Suppressor Genes：MSH2, PHB, TP53 (p53).