终末分化标志物基因表达 PCR 芯片可用于研究 84 个特定细胞类型鉴定关键基因的表达。该芯片为分化后细胞类型的鉴定提供了全面的解决方案,它包含了 13 种主要器官或细胞类型以及 7 种相对特殊细胞类型的各 1-3 个基因表达标志物。通过实时定量 PCR,研究者可以简单可靠地同时分析细胞类型鉴定相关基因的表达。
Adipocyte: ADIPOQ, FABP4, PPARG.
Chondrocyte: ACAN, COL10A1, COMP.
Endothelium: General: CDH5, KDR, PECAM1.
Arterial: DLL4, EFNB2, NRP1.
Lymphatic: LYVE1, PROX1.
Venous: NR2F2, NRP2.
Epithelium: Keinocyte: KRT1, KRT10, KRT14.
Melanocyte: PMEL, TYR, TYRP1.
Bone: Osteoblast: BGLAP, COL2A1, IBSP.
Osteoclast: CALCR, CTSK.
Liver: Cholangiocyte: ITGB4, KRT19.
HePAtocyte: ALB, G6PC, TAT.
Bone Marrow:
Early B cell Development: CD79A.
Early T Cell Development: CD3E, PTCRA.
Macrophage: CCR5, CXCR4, EMR1.
Monocyte: ITGAM.
Nervous System: Glial Cell: GALC, GFAP.
Mature Neuron: MAP2, NEFH, TUBB3.
Cholinergic Neuron: CHAT.
DoPAminergic Neuron: TH.
GABA Neuron: GAD1, SLC32A1.
Glutamatergic Neuron: SLC17A6, SLC17A7.
Motor Neuron: ISL1.
Oligodendrocyte: MBP.
Retina: Ganglion Cell: POU4F2.
Muller Cell: RLBP1.
Photoreceptor Cell: PDE6B, RCVRN.
Kidney (Nephron): Podocyte: NPHS2.
Proximal Tubule Cell: AQP1, CYP27B1, MIOX.
Collecting Duct Cell:AQP2.
Distal Tubule Cell: UMOD.
Lung: SFTPB, SFTPC, SFTPD.
Muscle: Cardiomyocyte: MYH6, MYH7, NPPA.
Skeletal Muscle Cell: CAV3, MYH1, MYOD1.
Smooth Muscle Cell: MYH11, SMTN, TAGLN.
PAncreas: Alpha Cell: GCG, MAFB, POU3F4.
Beta Cell: INS, MAFA, SLC2A2.
Delta Cell: SST.
Epsilon Cell: GHRL.
PP Cell: PPY.
Exocrine Cell: CPA1.